The Resource A handbook for DNA-encoded chemistry : theory and applications for exploring chemical space and drug discovery, edited by Robert A. Goodnow, Jr
A handbook for DNA-encoded chemistry : theory and applications for exploring chemical space and drug discovery, edited by Robert A. Goodnow, Jr
Resource Information
The item A handbook for DNA-encoded chemistry : theory and applications for exploring chemical space and drug discovery, edited by Robert A. Goodnow, Jr represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in Missouri University of Science & Technology Library.This item is available to borrow from 1 library branch.
Resource Information
The item A handbook for DNA-encoded chemistry : theory and applications for exploring chemical space and drug discovery, edited by Robert A. Goodnow, Jr represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in Missouri University of Science & Technology Library.
This item is available to borrow from 1 library branch.
- Summary
- This book comprehensively describes the development and practice of DNA-encoded library synthesis technology. Together, the chapters detail an approach to drug discovery that offers an attractive addition to the portfolio of existing hit generation technologies such as high-throughput screening, structure-based drug discovery and fragment-based screening. The book: Provides a valuable guide for understanding and applying DNA-encoded combinatorial chemistry Helps chemists generate and screen novel chemical libraries of large size and quality Bridges interdisciplinary areas of DNA-encoded combi
- Language
- eng
- Extent
- 1 online resource
- Contents
-
- Just enough knowledge?
- A brief history of the development of combinatorial chemistry and the emerging need for DNA-encoded chemistry
- A history of DNA-encoding
- DNA-compatible chemistry
- Foundations of a DNA-encoded library (DEL)
- Practices for synthesizing DNA-encoded libraries
- Chemical gene design for DNA-encoded libraries
- Analytical challenges for DNA-encoded library systems
- Information technology: functionality and architectures for DNA-encoding
- Theoretical considerations of the application of DNA-encoded libraries to drug discovery
- Begin with the end in mind : the hit-to-lead process
- Enumeration and visualization of large combinatorial chemical libraries
- Screening large compound collections
- Reported applications of DNA-encoded library chemistry
- Dual-pharmacophore DNA-encoded chemical libraries
- Hit identification and hit follow-up
- Using DNA to program chemical synthesis, discover new reactions, and detect ligand binding
- An outlook and the changing feasibility and economics of chemical diversity exploration with DNA-encoded combinatorial approaches
- Keeping the promise? an outlook on dna chemical library technology
- Isbn
- 9781306642514
- Label
- A handbook for DNA-encoded chemistry : theory and applications for exploring chemical space and drug discovery
- Title
- A handbook for DNA-encoded chemistry
- Title remainder
- theory and applications for exploring chemical space and drug discovery
- Statement of responsibility
- edited by Robert A. Goodnow, Jr
- Language
- eng
- Summary
- This book comprehensively describes the development and practice of DNA-encoded library synthesis technology. Together, the chapters detail an approach to drug discovery that offers an attractive addition to the portfolio of existing hit generation technologies such as high-throughput screening, structure-based drug discovery and fragment-based screening. The book: Provides a valuable guide for understanding and applying DNA-encoded combinatorial chemistry Helps chemists generate and screen novel chemical libraries of large size and quality Bridges interdisciplinary areas of DNA-encoded combi
- Cataloging source
- DLC
- Dewey number
- 615.1/9
- Index
- index present
- LC call number
- RS420
- Literary form
- non fiction
- Nature of contents
-
- dictionaries
- bibliography
- NLM call number
- QV 744
- http://library.link/vocab/relatedWorkOrContributorName
- Goodnow, Robert A.
- http://library.link/vocab/subjectName
-
- Combinatorial chemistry
- DNA
- Combinatorial Chemistry Techniques
- DNA
- Drug Discovery
- Gene Library
- Small Molecule Libraries
- MEDICAL
- DNA
- Label
- A handbook for DNA-encoded chemistry : theory and applications for exploring chemical space and drug discovery, edited by Robert A. Goodnow, Jr
- Bibliography note
- Includes bibliographical references and index
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Contents
- Just enough knowledge? -- A brief history of the development of combinatorial chemistry and the emerging need for DNA-encoded chemistry -- A history of DNA-encoding -- DNA-compatible chemistry -- Foundations of a DNA-encoded library (DEL) -- Practices for synthesizing DNA-encoded libraries -- Chemical gene design for DNA-encoded libraries -- Analytical challenges for DNA-encoded library systems -- Information technology: functionality and architectures for DNA-encoding -- Theoretical considerations of the application of DNA-encoded libraries to drug discovery -- Begin with the end in mind : the hit-to-lead process -- Enumeration and visualization of large combinatorial chemical libraries -- Screening large compound collections -- Reported applications of DNA-encoded library chemistry -- Dual-pharmacophore DNA-encoded chemical libraries -- Hit identification and hit follow-up -- Using DNA to program chemical synthesis, discover new reactions, and detect ligand binding -- An outlook and the changing feasibility and economics of chemical diversity exploration with DNA-encoded combinatorial approaches -- Keeping the promise? an outlook on dna chemical library technology
- Control code
- 863127741
- Extent
- 1 online resource
- Form of item
- online
- Isbn
- 9781306642514
- Lccn
- 2013046115
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- http://library.link/vocab/ext/overdrive/overdriveId
- ecbac530-4a08-4ebd-a06f-b8af5c902c02
- Specific material designation
- remote
- System control number
- (OCoLC)863127741
- Label
- A handbook for DNA-encoded chemistry : theory and applications for exploring chemical space and drug discovery, edited by Robert A. Goodnow, Jr
- Bibliography note
- Includes bibliographical references and index
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Contents
- Just enough knowledge? -- A brief history of the development of combinatorial chemistry and the emerging need for DNA-encoded chemistry -- A history of DNA-encoding -- DNA-compatible chemistry -- Foundations of a DNA-encoded library (DEL) -- Practices for synthesizing DNA-encoded libraries -- Chemical gene design for DNA-encoded libraries -- Analytical challenges for DNA-encoded library systems -- Information technology: functionality and architectures for DNA-encoding -- Theoretical considerations of the application of DNA-encoded libraries to drug discovery -- Begin with the end in mind : the hit-to-lead process -- Enumeration and visualization of large combinatorial chemical libraries -- Screening large compound collections -- Reported applications of DNA-encoded library chemistry -- Dual-pharmacophore DNA-encoded chemical libraries -- Hit identification and hit follow-up -- Using DNA to program chemical synthesis, discover new reactions, and detect ligand binding -- An outlook and the changing feasibility and economics of chemical diversity exploration with DNA-encoded combinatorial approaches -- Keeping the promise? an outlook on dna chemical library technology
- Control code
- 863127741
- Extent
- 1 online resource
- Form of item
- online
- Isbn
- 9781306642514
- Lccn
- 2013046115
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- http://library.link/vocab/ext/overdrive/overdriveId
- ecbac530-4a08-4ebd-a06f-b8af5c902c02
- Specific material designation
- remote
- System control number
- (OCoLC)863127741
Subject
- Small Molecule Libraries -- chemical synthesis
- Combinatorial Chemistry Techniques -- methods
- Combinatorial chemistry -- Technique
- DNA -- Synthesis
- DNA -- Synthesis
- DNA -- chemical synthesis
- Drug Discovery -- methods
- Electronic books
- Gene Library
- MEDICAL -- Pharmacology
- Methods (Music)
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<div class="citation" vocab="http://schema.org/"><i class="fa fa-external-link-square fa-fw"></i> Data from <span resource="http://link.library.mst.edu/portal/A-handbook-for-DNA-encoded-chemistry--theory-and/OJB9kNcM9pQ/" typeof="Book http://bibfra.me/vocab/lite/Item"><span property="name http://bibfra.me/vocab/lite/label"><a href="http://link.library.mst.edu/portal/A-handbook-for-DNA-encoded-chemistry--theory-and/OJB9kNcM9pQ/">A handbook for DNA-encoded chemistry : theory and applications for exploring chemical space and drug discovery, edited by Robert A. Goodnow, Jr</a></span> - <span property="potentialAction" typeOf="OrganizeAction"><span property="agent" typeof="LibrarySystem http://library.link/vocab/LibrarySystem" resource="http://link.library.mst.edu/"><span property="name http://bibfra.me/vocab/lite/label"><a property="url" href="http://link.library.mst.edu/">Missouri University of Science & Technology Library</a></span></span></span></span></div>