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The Resource Biologically-responsive hybrid biomaterials : a reference for material scientists and bioengineers, editors, E. Jabbari, A. Khademhosseini

Biologically-responsive hybrid biomaterials : a reference for material scientists and bioengineers, editors, E. Jabbari, A. Khademhosseini

Contributor
Summary
Conjugation of synthetic materials with cell-responsive biologically-active molecules, in addition to providing structural support and release of biomolecules in the regenerating region, can provide the signaling factors required to initiate the cascade of cell migration, adhesion, differentiation, maturation, growth factor modulation, maintenance of matrix integrity, and tissue morphogenesis. Nanoparticles conjugated with ligands that preferentially interact with cell surface receptors in the tumor environment have the potential to drastically improve bioavailability, selectivity and residence time of the chemotherapeutic agent in the tumor microenvironment, while limiting their peripheral toxicity. Multivalent presentation of tumor-associated antigens on a targeted delivery system containing T and B cell epitopes can result in strong, long-lasting, self-adjuvant immunity against cancer and other diseases in vaccination. These examples demonstrate that cell-responsive conjugate biomaterials have profoundly impacted the medical field. This book is divided into three sections. In the first section, synthesis and characterization, conformation, structure-activity, self-assembly, and host response of conjugate hybrid biomaterials are covered. The second section is dedicated to the applications of conjugate biomaterials in drug delivery and vaccination while the last section is devoted to tissue engineering applications including cell adhesion, control of the stem cell niche, cartilage regeneration, neural and vascular tissue engineering, and dynamic cell culture systems for functionalized biomaterials. There is no doubt that biologically-responsive conjugate biomaterials play a key role in the design of biologics and medical devices, and this pioneering reference book provides a comprehensive review on synthesis, characterization, structure-activity, 3D assembly/fabrication, host response and the emerging applications of conjugate hybrid biomaterials
Language
eng
Work
Publication
Extent
1 online resource (vi, 423 pages)
Contents
  • Engineering the tissue extracellular matrix with hybrid biomaterials
  • Synthesis, characterization and self-assembly
  • Bulk and solution properties of peptide-polymer conjugates
  • Polymer-peptide conjugate networks: formation, swelling and degradation
  • Peptide self-assembly biomaterials design and application
  • Micropatterned polymer structures for cell and tissue engineering
  • Synthesis and in vitro/in vivo response to peptide-polymer conjugates
  • Hybrid biomaterials in drug delivery and molecular recognition
  • Synthesis of multi-epitopic glycopeptide-based cancer vaccines
  • Stimuli-sensitive particles for drug delivery
  • Design and synthesis of endosomolytic conjugated polyaspartamide for cytosolic drug delivery
  • Engineering of cell-penetrating peptide-conjugated intracellular delivery systems
  • Cell responsive biomaterials in tissue engineering
  • Biomimetic matrices for integrin-mediated cell adhesion
  • Engineering artificial stem cell niches
  • Engineering peptides in hydrogels for cartilage tissue regeneration
  • Biomimetic materials for engineering of neural tissues: control of cell adhesion and guiding neural cell outgrowth with peptide-conjugated polymer structures
  • Hybrid biomaterials for engineering vascular tissues
  • Dynamic cell culture methods for functionalized biomaterials
Isbn
9789814295680
Instance
Label
Biologically-responsive hybrid biomaterials : a reference for material scientists and bioengineers
Title
Biologically-responsive hybrid biomaterials
Title remainder
a reference for material scientists and bioengineers
Statement of responsibility
editors, E. Jabbari, A. Khademhosseini
Contributor
Subject
Genre
Language
eng
Summary
Conjugation of synthetic materials with cell-responsive biologically-active molecules, in addition to providing structural support and release of biomolecules in the regenerating region, can provide the signaling factors required to initiate the cascade of cell migration, adhesion, differentiation, maturation, growth factor modulation, maintenance of matrix integrity, and tissue morphogenesis. Nanoparticles conjugated with ligands that preferentially interact with cell surface receptors in the tumor environment have the potential to drastically improve bioavailability, selectivity and residence time of the chemotherapeutic agent in the tumor microenvironment, while limiting their peripheral toxicity. Multivalent presentation of tumor-associated antigens on a targeted delivery system containing T and B cell epitopes can result in strong, long-lasting, self-adjuvant immunity against cancer and other diseases in vaccination. These examples demonstrate that cell-responsive conjugate biomaterials have profoundly impacted the medical field. This book is divided into three sections. In the first section, synthesis and characterization, conformation, structure-activity, self-assembly, and host response of conjugate hybrid biomaterials are covered. The second section is dedicated to the applications of conjugate biomaterials in drug delivery and vaccination while the last section is devoted to tissue engineering applications including cell adhesion, control of the stem cell niche, cartilage regeneration, neural and vascular tissue engineering, and dynamic cell culture systems for functionalized biomaterials. There is no doubt that biologically-responsive conjugate biomaterials play a key role in the design of biologics and medical devices, and this pioneering reference book provides a comprehensive review on synthesis, characterization, structure-activity, 3D assembly/fabrication, host response and the emerging applications of conjugate hybrid biomaterials
Member of
Cataloging source
N$T
Dewey number
610.28
Illustrations
illustrations
Index
index present
LC call number
R857.M3
LC item number
B4767 2010eb
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
  • 2010 G-444
  • QT 37
http://library.link/vocab/relatedWorkOrContributorName
  • Jabbari, E.
  • Khademhosseini, Ali
http://library.link/vocab/subjectName
  • Biomedical materials
  • Cells
  • Biochemical Phenomena
  • Culture Techniques
  • Pharmacological Phenomena
  • Biomedical and Dental Materials
  • Drug Therapy
  • Biomimetic Materials
  • Cells, Cultured
  • Structure-Activity Relationship
  • Biocompatible Materials
  • Tissue Engineering
  • Drug Delivery Systems
  • Technology, Industry, and Agriculture
  • Clinical Laboratory Techniques
  • Therapeutics
  • Chemical Phenomena
  • Specialty Uses of Chemicals
  • Physiological Phenomena
  • Anatomy
  • Investigative Techniques
  • Chemical Actions and Uses
  • Manufactured Materials
  • TECHNOLOGY & ENGINEERING
  • MEDICAL
  • MEDICAL
  • MEDICAL
  • MEDICAL
  • Biomedical materials
Label
Biologically-responsive hybrid biomaterials : a reference for material scientists and bioengineers, editors, E. Jabbari, A. Khademhosseini
Instantiates
Publication
Antecedent source
unknown
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
mixed
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Engineering the tissue extracellular matrix with hybrid biomaterials -- Synthesis, characterization and self-assembly -- Bulk and solution properties of peptide-polymer conjugates -- Polymer-peptide conjugate networks: formation, swelling and degradation -- Peptide self-assembly biomaterials design and application -- Micropatterned polymer structures for cell and tissue engineering -- Synthesis and in vitro/in vivo response to peptide-polymer conjugates -- Hybrid biomaterials in drug delivery and molecular recognition -- Synthesis of multi-epitopic glycopeptide-based cancer vaccines -- Stimuli-sensitive particles for drug delivery -- Design and synthesis of endosomolytic conjugated polyaspartamide for cytosolic drug delivery -- Engineering of cell-penetrating peptide-conjugated intracellular delivery systems -- Cell responsive biomaterials in tissue engineering -- Biomimetic matrices for integrin-mediated cell adhesion -- Engineering artificial stem cell niches -- Engineering peptides in hydrogels for cartilage tissue regeneration -- Biomimetic materials for engineering of neural tissues: control of cell adhesion and guiding neural cell outgrowth with peptide-conjugated polymer structures -- Hybrid biomaterials for engineering vascular tissues -- Dynamic cell culture methods for functionalized biomaterials
Control code
681789053
Dimensions
unknown
Extent
1 online resource (vi, 423 pages)
File format
unknown
Form of item
online
Isbn
9789814295680
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations (some color)
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
(OCoLC)681789053
Label
Biologically-responsive hybrid biomaterials : a reference for material scientists and bioengineers, editors, E. Jabbari, A. Khademhosseini
Publication
Antecedent source
unknown
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
mixed
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Engineering the tissue extracellular matrix with hybrid biomaterials -- Synthesis, characterization and self-assembly -- Bulk and solution properties of peptide-polymer conjugates -- Polymer-peptide conjugate networks: formation, swelling and degradation -- Peptide self-assembly biomaterials design and application -- Micropatterned polymer structures for cell and tissue engineering -- Synthesis and in vitro/in vivo response to peptide-polymer conjugates -- Hybrid biomaterials in drug delivery and molecular recognition -- Synthesis of multi-epitopic glycopeptide-based cancer vaccines -- Stimuli-sensitive particles for drug delivery -- Design and synthesis of endosomolytic conjugated polyaspartamide for cytosolic drug delivery -- Engineering of cell-penetrating peptide-conjugated intracellular delivery systems -- Cell responsive biomaterials in tissue engineering -- Biomimetic matrices for integrin-mediated cell adhesion -- Engineering artificial stem cell niches -- Engineering peptides in hydrogels for cartilage tissue regeneration -- Biomimetic materials for engineering of neural tissues: control of cell adhesion and guiding neural cell outgrowth with peptide-conjugated polymer structures -- Hybrid biomaterials for engineering vascular tissues -- Dynamic cell culture methods for functionalized biomaterials
Control code
681789053
Dimensions
unknown
Extent
1 online resource (vi, 423 pages)
File format
unknown
Form of item
online
Isbn
9789814295680
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations (some color)
Quality assurance targets
not applicable
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
(OCoLC)681789053

Subject

Genre

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