The Resource Development and evaluation of a novel germanium-68/gallium-68 generator, by Yu-Wen Chang, (electronic resource)
Development and evaluation of a novel germanium-68/gallium-68 generator, by Yu-Wen Chang, (electronic resource)
Resource Information
The item Development and evaluation of a novel germanium-68/gallium-68 generator, by Yu-Wen Chang, (electronic resource) represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in Missouri University of Science & Technology Library.This item is available to borrow from 1 library branch.
Resource Information
The item Development and evaluation of a novel germanium-68/gallium-68 generator, by Yu-Wen Chang, (electronic resource) represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in Missouri University of Science & Technology Library.
This item is available to borrow from 1 library branch.
- Summary
- The aim of this research is to evaluate Fajans adsorption technique to deliver 68Ga in a high concentration, low volume with minimal impurities including 68Ge breakthrough and other metals. First carrier-free stock solutions and stock solutions containing three different concentrations of carrier were tested. Here the stock solution containing 68Ge:Ge ratio of 1:20K, 1:200K, and 1:2KK was represented as 20K, 200K and 2KK fold carrier-added stock solution respectively. The optimized concentration level of carrier was utilized for further tests at four different pH values and two different buffers. The Fajans system was evaluated with two different adsorbents and two column bed sizes. In addition, we investigated a carrier-free with acetone added stock solution. The optimized conditions were determined to be that the 200K fold carrier stock solution in NaOAc buffer at pH 5.6 is the most suitable condition for 1.0 ml BSi beads to obtain the highest 68Ga yield (90%) and the lowest 68Ge breakthrough (0.009%) in the daughter product. At pH 5.6 stock solutions, the optimized conditions for acetone added stock solution were determined to be 10% acetone at NH4OAc buffer for 1.0 ml BSi beads (92% 68Ga yield and 0.04% 68Ge breakthrough) and 50% acetone at NH4OAc buffer for 0.2 ml BSi beads (82% 68Ga yield and 0.03% 68Ge breakthrough). The addition of carrier germanium to the 68Ge/68Ga solution did help in decreasing the amount of 68Ge detected in the wash and strip solutions. The progressive lowering of metals detected in the strip solutions collected from the BSi beads Fajans adsorption generator points towards a very workable separation system
- Language
- eng
- Extent
- 1 online resource (xi, 67 pages)
- Note
-
- The entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file
- Title from PDF of title page (University of Missouri--Columbia, viewed on January 28, 2011)
- Thesis advisor: Dr. Cathy S. Cutler
- Vita
- Label
- Development and evaluation of a novel germanium-68/gallium-68 generator
- Title
- Development and evaluation of a novel germanium-68/gallium-68 generator
- Statement of responsibility
- by Yu-Wen Chang
- Language
- eng
- Summary
- The aim of this research is to evaluate Fajans adsorption technique to deliver 68Ga in a high concentration, low volume with minimal impurities including 68Ge breakthrough and other metals. First carrier-free stock solutions and stock solutions containing three different concentrations of carrier were tested. Here the stock solution containing 68Ge:Ge ratio of 1:20K, 1:200K, and 1:2KK was represented as 20K, 200K and 2KK fold carrier-added stock solution respectively. The optimized concentration level of carrier was utilized for further tests at four different pH values and two different buffers. The Fajans system was evaluated with two different adsorbents and two column bed sizes. In addition, we investigated a carrier-free with acetone added stock solution. The optimized conditions were determined to be that the 200K fold carrier stock solution in NaOAc buffer at pH 5.6 is the most suitable condition for 1.0 ml BSi beads to obtain the highest 68Ga yield (90%) and the lowest 68Ge breakthrough (0.009%) in the daughter product. At pH 5.6 stock solutions, the optimized conditions for acetone added stock solution were determined to be 10% acetone at NH4OAc buffer for 1.0 ml BSi beads (92% 68Ga yield and 0.04% 68Ge breakthrough) and 50% acetone at NH4OAc buffer for 0.2 ml BSi beads (82% 68Ga yield and 0.03% 68Ge breakthrough). The addition of carrier germanium to the 68Ge/68Ga solution did help in decreasing the amount of 68Ge detected in the wash and strip solutions. The progressive lowering of metals detected in the strip solutions collected from the BSi beads Fajans adsorption generator points towards a very workable separation system
- Cataloging source
- MUU
- http://library.link/vocab/creatorDate
- 1980-
- http://library.link/vocab/creatorName
- Chang, Yu-Wen
- Degree
- Ph. D.
- Dissertation year
- 2009.
- Granting institution
- University of Missouri--Columbia
- Index
- no index present
- Literary form
- non fiction
- Nature of contents
-
- dictionaries
- bibliography
- theses
- http://library.link/vocab/relatedWorkOrContributorName
- Cutler, Cathy S.
- http://library.link/vocab/subjectName
-
- Germanium
- Gallium
- Radionuclide generators
- Tomography, Emission
- Target audience
- specialized
- Label
- Development and evaluation of a novel germanium-68/gallium-68 generator, by Yu-Wen Chang, (electronic resource)
- Note
-
- The entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file
- Title from PDF of title page (University of Missouri--Columbia, viewed on January 28, 2011)
- Thesis advisor: Dr. Cathy S. Cutler
- Vita
- Bibliography note
- Includes bibliographical references
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Control code
- 698780427
- Extent
- 1 online resource (xi, 67 pages)
- Form of item
- online
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- Note
- MU: Access is limited to the campuses of the University of Missouri.
- Specific material designation
- remote
- System control number
- (OCoLC)698780427
- Label
- Development and evaluation of a novel germanium-68/gallium-68 generator, by Yu-Wen Chang, (electronic resource)
- Note
-
- The entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file
- Title from PDF of title page (University of Missouri--Columbia, viewed on January 28, 2011)
- Thesis advisor: Dr. Cathy S. Cutler
- Vita
- Bibliography note
- Includes bibliographical references
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Control code
- 698780427
- Extent
- 1 online resource (xi, 67 pages)
- Form of item
- online
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- Note
- MU: Access is limited to the campuses of the University of Missouri.
- Specific material designation
- remote
- System control number
- (OCoLC)698780427
Library Links
Embed
Settings
Select options that apply then copy and paste the RDF/HTML data fragment to include in your application
Embed this data in a secure (HTTPS) page:
Layout options:
Include data citation:
<div class="citation" vocab="http://schema.org/"><i class="fa fa-external-link-square fa-fw"></i> Data from <span resource="http://link.library.mst.edu/portal/Development-and-evaluation-of-a-novel/QfdIVv0Mdl8/" typeof="Book http://bibfra.me/vocab/lite/Item"><span property="name http://bibfra.me/vocab/lite/label"><a href="http://link.library.mst.edu/portal/Development-and-evaluation-of-a-novel/QfdIVv0Mdl8/">Development and evaluation of a novel germanium-68/gallium-68 generator, by Yu-Wen Chang, (electronic resource)</a></span> - <span property="potentialAction" typeOf="OrganizeAction"><span property="agent" typeof="LibrarySystem http://library.link/vocab/LibrarySystem" resource="http://link.library.mst.edu/"><span property="name http://bibfra.me/vocab/lite/label"><a property="url" href="http://link.library.mst.edu/">Missouri University of Science & Technology Library</a></span></span></span></span></div>
Note: Adjust the width and height settings defined in the RDF/HTML code fragment to best match your requirements
Preview
Cite Data - Experimental
Data Citation of the Item Development and evaluation of a novel germanium-68/gallium-68 generator, by Yu-Wen Chang, (electronic resource)
Copy and paste the following RDF/HTML data fragment to cite this resource
<div class="citation" vocab="http://schema.org/"><i class="fa fa-external-link-square fa-fw"></i> Data from <span resource="http://link.library.mst.edu/portal/Development-and-evaluation-of-a-novel/QfdIVv0Mdl8/" typeof="Book http://bibfra.me/vocab/lite/Item"><span property="name http://bibfra.me/vocab/lite/label"><a href="http://link.library.mst.edu/portal/Development-and-evaluation-of-a-novel/QfdIVv0Mdl8/">Development and evaluation of a novel germanium-68/gallium-68 generator, by Yu-Wen Chang, (electronic resource)</a></span> - <span property="potentialAction" typeOf="OrganizeAction"><span property="agent" typeof="LibrarySystem http://library.link/vocab/LibrarySystem" resource="http://link.library.mst.edu/"><span property="name http://bibfra.me/vocab/lite/label"><a property="url" href="http://link.library.mst.edu/">Missouri University of Science & Technology Library</a></span></span></span></span></div>
