Coverart for item
The Resource Evaluation of drug candidates for preclinical development : pharmacokinetics, metabolism, pharmaceutics, and toxicology, [edited by] Chao Han, Charles B. Davis, Binghe Wang

Evaluation of drug candidates for preclinical development : pharmacokinetics, metabolism, pharmaceutics, and toxicology, [edited by] Chao Han, Charles B. Davis, Binghe Wang

Label
Evaluation of drug candidates for preclinical development : pharmacokinetics, metabolism, pharmaceutics, and toxicology
Title
Evaluation of drug candidates for preclinical development
Title remainder
pharmacokinetics, metabolism, pharmaceutics, and toxicology
Statement of responsibility
[edited by] Chao Han, Charles B. Davis, Binghe Wang
Contributor
Subject
Language
eng
Summary
Explaining the assessment of potential drug compounds, this is an ideal introductory reference for those new to drug discovery. It includes sections on pharmacokinetics and drug metabolism, integration of pharmaceutical development, and predictive safety assessment. Topics include: cost analysis, drug transporters, cytochrome P-450 and drug-drug interactions, plasma protein binding, assessing stability, ways to optimize drug formulation, toxicology and toxicokinetics, and more. Readers will understand why absorption-distribution-metabolism-excretion-toxicology (ADMET) is key in drug developmen
Member of
Cataloging source
DG1
Dewey number
615/.19
Index
index present
LC call number
RM301.25
LC item number
.E93 2010
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
  • 2010 C-003
  • QV 771
NLM item number
E917 2010
http://library.link/vocab/relatedWorkOrContributorDate
1962-
http://library.link/vocab/relatedWorkOrContributorName
  • Han, Chao
  • Davis, Charles B.
  • Wang, Binghe
Series statement
Wiley series in drug discovery and development
http://library.link/vocab/subjectName
  • Drug development
  • Pharmacokinetics
  • Drugs
  • Drug Evaluation, Preclinical
  • Drug Discovery
  • Drug Industry
  • Pharmaceutical Preparations
  • Pharmacology
  • MEDICAL
  • MEDICAL
  • MEDICAL
  • MEDICAL
  • Drug development
  • Drugs
  • Pharmacokinetics
Label
Evaluation of drug candidates for preclinical development : pharmacokinetics, metabolism, pharmaceutics, and toxicology, [edited by] Chao Han, Charles B. Davis, Binghe Wang
Instantiates
Publication
Note
Includes index
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Pharmacokinetics in preclinical drug development : an overview / Dion Brocks -- The role of membrane transporters in drug disposition / Fanfan Zhou, Peng Duan, and Guofeng You -- Cytochrome P450 : structure, function, and application in drug discovery and development / Ramesh B. Bambal and Stephen E. Clarke -- The role of drug metabolism and metabolite identification in drug discovery / Xiangming Guan -- Protein binding in drug discovery and development / Vikram Ramanathan and Nimish Vachharajani -- Prediction of the pharmacokinetics in humans / Chao Han and Remash Bambal -- Pharmaceutics developability assessment / Lian Huang, Jinquan Dong, and Shyam Karki -- Safety assessment in drug discovery / Vito G. Sasseville, William R. Foster, Bruce D. Car -- Assessment of strategies utilized to minimize the potential for induction of acquired long QT syndrome and torsade de pointes / Khuram W. Chaudhary and Barry S. Brown
Control code
501316330
Dimensions
unknown
Extent
1 online resource
Form of item
online
Isbn
9781282684904
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1002/9780470574898
http://library.link/vocab/ext/overdrive/overdriveId
10.1002/9780470574898
Specific material designation
remote
System control number
(OCoLC)501316330
Label
Evaluation of drug candidates for preclinical development : pharmacokinetics, metabolism, pharmaceutics, and toxicology, [edited by] Chao Han, Charles B. Davis, Binghe Wang
Publication
Note
Includes index
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Pharmacokinetics in preclinical drug development : an overview / Dion Brocks -- The role of membrane transporters in drug disposition / Fanfan Zhou, Peng Duan, and Guofeng You -- Cytochrome P450 : structure, function, and application in drug discovery and development / Ramesh B. Bambal and Stephen E. Clarke -- The role of drug metabolism and metabolite identification in drug discovery / Xiangming Guan -- Protein binding in drug discovery and development / Vikram Ramanathan and Nimish Vachharajani -- Prediction of the pharmacokinetics in humans / Chao Han and Remash Bambal -- Pharmaceutics developability assessment / Lian Huang, Jinquan Dong, and Shyam Karki -- Safety assessment in drug discovery / Vito G. Sasseville, William R. Foster, Bruce D. Car -- Assessment of strategies utilized to minimize the potential for induction of acquired long QT syndrome and torsade de pointes / Khuram W. Chaudhary and Barry S. Brown
Control code
501316330
Dimensions
unknown
Extent
1 online resource
Form of item
online
Isbn
9781282684904
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1002/9780470574898
http://library.link/vocab/ext/overdrive/overdriveId
10.1002/9780470574898
Specific material designation
remote
System control number
(OCoLC)501316330

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