The Resource Evaluation of drug candidates for preclinical development : pharmacokinetics, metabolism, pharmaceutics, and toxicology, [edited by] Chao Han, Charles B. Davis, Binghe Wang
Evaluation of drug candidates for preclinical development : pharmacokinetics, metabolism, pharmaceutics, and toxicology, [edited by] Chao Han, Charles B. Davis, Binghe Wang
Resource Information
The item Evaluation of drug candidates for preclinical development : pharmacokinetics, metabolism, pharmaceutics, and toxicology, [edited by] Chao Han, Charles B. Davis, Binghe Wang represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in Missouri University of Science & Technology Library.This item is available to borrow from 1 library branch.
Resource Information
The item Evaluation of drug candidates for preclinical development : pharmacokinetics, metabolism, pharmaceutics, and toxicology, [edited by] Chao Han, Charles B. Davis, Binghe Wang represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in Missouri University of Science & Technology Library.
This item is available to borrow from 1 library branch.
- Summary
- Explaining the assessment of potential drug compounds, this is an ideal introductory reference for those new to drug discovery. It includes sections on pharmacokinetics and drug metabolism, integration of pharmaceutical development, and predictive safety assessment. Topics include: cost analysis, drug transporters, cytochrome P-450 and drug-drug interactions, plasma protein binding, assessing stability, ways to optimize drug formulation, toxicology and toxicokinetics, and more. Readers will understand why absorption-distribution-metabolism-excretion-toxicology (ADMET) is key in drug developmen
- Language
- eng
- Extent
- 1 online resource
- Note
- Includes index
- Contents
-
- Pharmacokinetics in preclinical drug development : an overview / Dion Brocks
- The role of membrane transporters in drug disposition / Fanfan Zhou, Peng Duan, and Guofeng You
- Cytochrome P450 : structure, function, and application in drug discovery and development / Ramesh B. Bambal and Stephen E. Clarke
- The role of drug metabolism and metabolite identification in drug discovery / Xiangming Guan
- Protein binding in drug discovery and development / Vikram Ramanathan and Nimish Vachharajani
- Prediction of the pharmacokinetics in humans / Chao Han and Remash Bambal
- Pharmaceutics developability assessment / Lian Huang, Jinquan Dong, and Shyam Karki
- Safety assessment in drug discovery / Vito G. Sasseville, William R. Foster, Bruce D. Car
- Assessment of strategies utilized to minimize the potential for induction of acquired long QT syndrome and torsade de pointes / Khuram W. Chaudhary and Barry S. Brown
- Isbn
- 9781282684904
- Label
- Evaluation of drug candidates for preclinical development : pharmacokinetics, metabolism, pharmaceutics, and toxicology
- Title
- Evaluation of drug candidates for preclinical development
- Title remainder
- pharmacokinetics, metabolism, pharmaceutics, and toxicology
- Statement of responsibility
- [edited by] Chao Han, Charles B. Davis, Binghe Wang
- Subject
-
- Pharmacology -- methods
- Drug Discovery
- Drug Evaluation, Preclinical
- Drug Industry -- standards
- Drug development
- Drug development
- Drugs -- Metabolism
- Drugs -- Metabolism
- Electronic book
- Electronic books
- Electronic books
- MEDICAL -- Drug Guides
- MEDICAL -- Nursing | Pharmacology
- MEDICAL -- Pharmacology
- MEDICAL -- Pharmacy
- Pharmaceutical Preparations -- metabolism
- Pharmacokinetics
- Pharmacokinetics
- Language
- eng
- Summary
- Explaining the assessment of potential drug compounds, this is an ideal introductory reference for those new to drug discovery. It includes sections on pharmacokinetics and drug metabolism, integration of pharmaceutical development, and predictive safety assessment. Topics include: cost analysis, drug transporters, cytochrome P-450 and drug-drug interactions, plasma protein binding, assessing stability, ways to optimize drug formulation, toxicology and toxicokinetics, and more. Readers will understand why absorption-distribution-metabolism-excretion-toxicology (ADMET) is key in drug developmen
- Cataloging source
- DG1
- Dewey number
- 615/.19
- Index
- index present
- LC call number
- RM301.25
- LC item number
- .E93 2010
- Literary form
- non fiction
- Nature of contents
-
- dictionaries
- bibliography
- NLM call number
-
- 2010 C-003
- QV 771
- NLM item number
- E917 2010
- http://library.link/vocab/relatedWorkOrContributorDate
- 1962-
- http://library.link/vocab/relatedWorkOrContributorName
-
- Han, Chao
- Davis, Charles B.
- Wang, Binghe
- Series statement
- Wiley series in drug discovery and development
- http://library.link/vocab/subjectName
-
- Drug development
- Pharmacokinetics
- Drugs
- Drug Evaluation, Preclinical
- Drug Discovery
- Drug Industry
- Pharmaceutical Preparations
- Pharmacology
- MEDICAL
- MEDICAL
- MEDICAL
- MEDICAL
- Drug development
- Drugs
- Pharmacokinetics
- Label
- Evaluation of drug candidates for preclinical development : pharmacokinetics, metabolism, pharmaceutics, and toxicology, [edited by] Chao Han, Charles B. Davis, Binghe Wang
- Note
- Includes index
- Bibliography note
- Includes bibliographical references and index
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Color
- multicolored
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Contents
- Pharmacokinetics in preclinical drug development : an overview / Dion Brocks -- The role of membrane transporters in drug disposition / Fanfan Zhou, Peng Duan, and Guofeng You -- Cytochrome P450 : structure, function, and application in drug discovery and development / Ramesh B. Bambal and Stephen E. Clarke -- The role of drug metabolism and metabolite identification in drug discovery / Xiangming Guan -- Protein binding in drug discovery and development / Vikram Ramanathan and Nimish Vachharajani -- Prediction of the pharmacokinetics in humans / Chao Han and Remash Bambal -- Pharmaceutics developability assessment / Lian Huang, Jinquan Dong, and Shyam Karki -- Safety assessment in drug discovery / Vito G. Sasseville, William R. Foster, Bruce D. Car -- Assessment of strategies utilized to minimize the potential for induction of acquired long QT syndrome and torsade de pointes / Khuram W. Chaudhary and Barry S. Brown
- Control code
- 501316330
- Dimensions
- unknown
- Extent
- 1 online resource
- Form of item
- online
- Isbn
- 9781282684904
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- Other control number
- 10.1002/9780470574898
- http://library.link/vocab/ext/overdrive/overdriveId
- 10.1002/9780470574898
- Specific material designation
- remote
- System control number
- (OCoLC)501316330
- Label
- Evaluation of drug candidates for preclinical development : pharmacokinetics, metabolism, pharmaceutics, and toxicology, [edited by] Chao Han, Charles B. Davis, Binghe Wang
- Note
- Includes index
- Bibliography note
- Includes bibliographical references and index
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Color
- multicolored
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Contents
- Pharmacokinetics in preclinical drug development : an overview / Dion Brocks -- The role of membrane transporters in drug disposition / Fanfan Zhou, Peng Duan, and Guofeng You -- Cytochrome P450 : structure, function, and application in drug discovery and development / Ramesh B. Bambal and Stephen E. Clarke -- The role of drug metabolism and metabolite identification in drug discovery / Xiangming Guan -- Protein binding in drug discovery and development / Vikram Ramanathan and Nimish Vachharajani -- Prediction of the pharmacokinetics in humans / Chao Han and Remash Bambal -- Pharmaceutics developability assessment / Lian Huang, Jinquan Dong, and Shyam Karki -- Safety assessment in drug discovery / Vito G. Sasseville, William R. Foster, Bruce D. Car -- Assessment of strategies utilized to minimize the potential for induction of acquired long QT syndrome and torsade de pointes / Khuram W. Chaudhary and Barry S. Brown
- Control code
- 501316330
- Dimensions
- unknown
- Extent
- 1 online resource
- Form of item
- online
- Isbn
- 9781282684904
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- Other control number
- 10.1002/9780470574898
- http://library.link/vocab/ext/overdrive/overdriveId
- 10.1002/9780470574898
- Specific material designation
- remote
- System control number
- (OCoLC)501316330
Subject
- Pharmacology -- methods
- Drug Discovery
- Drug Evaluation, Preclinical
- Drug Industry -- standards
- Drug development
- Drug development
- Drugs -- Metabolism
- Drugs -- Metabolism
- Electronic book
- Electronic books
- Electronic books
- MEDICAL -- Drug Guides
- MEDICAL -- Nursing | Pharmacology
- MEDICAL -- Pharmacology
- MEDICAL -- Pharmacy
- Pharmaceutical Preparations -- metabolism
- Pharmacokinetics
- Pharmacokinetics
Genre
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<div class="citation" vocab="http://schema.org/"><i class="fa fa-external-link-square fa-fw"></i> Data from <span resource="http://link.library.mst.edu/portal/Evaluation-of-drug-candidates-for-preclinical/wu4spDz8Clc/" typeof="Book http://bibfra.me/vocab/lite/Item"><span property="name http://bibfra.me/vocab/lite/label"><a href="http://link.library.mst.edu/portal/Evaluation-of-drug-candidates-for-preclinical/wu4spDz8Clc/">Evaluation of drug candidates for preclinical development : pharmacokinetics, metabolism, pharmaceutics, and toxicology, [edited by] Chao Han, Charles B. Davis, Binghe Wang</a></span> - <span property="potentialAction" typeOf="OrganizeAction"><span property="agent" typeof="LibrarySystem http://library.link/vocab/LibrarySystem" resource="http://link.library.mst.edu/"><span property="name http://bibfra.me/vocab/lite/label"><a property="url" href="http://link.library.mst.edu/">Missouri University of Science & Technology Library</a></span></span></span></span></div>
