Coverart for item
The Resource Heritable human genome editing, International Commission on the Clinical Use of Human Germline Genome Editing ; National Academy of Medicine ; National Academy of Sciences ; and the Royal Society

Heritable human genome editing, International Commission on the Clinical Use of Human Germline Genome Editing ; National Academy of Medicine ; National Academy of Sciences ; and the Royal Society

Label
Heritable human genome editing
Title
Heritable human genome editing
Statement of responsibility
International Commission on the Clinical Use of Human Germline Genome Editing ; National Academy of Medicine ; National Academy of Sciences ; and the Royal Society
Title variation
Human genome
Contributor
Issuing body
Subject
Language
eng
Summary
"Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight."--
Member of
Assigning source
Publisher's website
Cataloging source
NLM
Dewey number
572.86
Funding information
This activity was supported by Contract No. HHSN263201800029I / Order No. 75N98019F00852 from the U.S. National Institutes of Health, Grant No. 2019 HTH 009 from the Rockefeller Foundation, and Grant 218375/Z/19/Z from the Wellcome Trust, with additional support from the Royal Society of the United Kingdom, the Cicerone Endowment Fund of the U.S. National Academy of Sciences, and the NAM Initiatives Fund of the U.S. National Academy of Medicine. Any opinions, findings, conclusions, or recommendations expressed in this publication do not necessarily reflect the views of any organization or agency that provided support for the project.
Illustrations
illustrations
Index
no index present
LC call number
QH447
LC item number
.H4758 2020
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
QU 470
http://library.link/vocab/relatedWorkOrContributorName
International Commission on the Clinical Use of Human Germline Genome Editing
Series statement
Consensus study report
http://library.link/vocab/subjectName
  • Human genome
  • Gene editing
  • Ethics
  • Gene Editing
  • Genome
  • Quantitative Trait, Heritable
  • Genomics
  • Ethics
  • Gene editing
  • Human genome
Label
Heritable human genome editing, International Commission on the Clinical Use of Human Germline Genome Editing ; National Academy of Medicine ; National Academy of Sciences ; and the Royal Society
Instantiates
Publication
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Intro -- FrontMatter -- Special Acknowledgments -- Foreword -- Contents -- Boxes and Figures -- Summary -- 1 Introduction -- 2 The State of the Science -- 3 Potential Applications of Heritable Human Genome Editing -- 4 A Translational Pathway to Limited and Controlled Clinical Applications of Heritable Human Genome Editing -- 5 National and International Governance of Heritable Human Genome Editing -- References -- Appendix A: Information Sources and Methods -- Appendix B: Commissioner Biographies -- Appendix C: Glossary -- Appendix D: Acronyms and Abbreviations -- Acknowledgment of Reviewers
Control code
on1227386525
Dimensions
unknown
Extent
1 online resource (1 PDF file (xviii, 219 pages))
Form of item
online
Isbn
9780309671163
Lccn
2020949045
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
color illustrations.
Specific material designation
remote
System control number
(OCoLC)1227386525
Label
Heritable human genome editing, International Commission on the Clinical Use of Human Germline Genome Editing ; National Academy of Medicine ; National Academy of Sciences ; and the Royal Society
Publication
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Intro -- FrontMatter -- Special Acknowledgments -- Foreword -- Contents -- Boxes and Figures -- Summary -- 1 Introduction -- 2 The State of the Science -- 3 Potential Applications of Heritable Human Genome Editing -- 4 A Translational Pathway to Limited and Controlled Clinical Applications of Heritable Human Genome Editing -- 5 National and International Governance of Heritable Human Genome Editing -- References -- Appendix A: Information Sources and Methods -- Appendix B: Commissioner Biographies -- Appendix C: Glossary -- Appendix D: Acronyms and Abbreviations -- Acknowledgment of Reviewers
Control code
on1227386525
Dimensions
unknown
Extent
1 online resource (1 PDF file (xviii, 219 pages))
Form of item
online
Isbn
9780309671163
Lccn
2020949045
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
color illustrations.
Specific material designation
remote
System control number
(OCoLC)1227386525

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