Coverart for item
The Resource Molecular diagnostics : current research and applications, edited by Jim F. Huggett and Justin O'Grady

Molecular diagnostics : current research and applications, edited by Jim F. Huggett and Justin O'Grady

Label
Molecular diagnostics : current research and applications
Title
Molecular diagnostics
Title remainder
current research and applications
Statement of responsibility
edited by Jim F. Huggett and Justin O'Grady
Contributor
Editor
Subject
Genre
Language
eng
Summary
The application of molecular technology in clinical diagnosis is a rapidly developing area and is predicted to greatly improve the speed, efficiency, and accuracy of diagnostic medicine. The editors of this book have commissioned an excellent series of chapters representing two key molecular diagnostic areas: cancer and infectious diseases. The cancer section deals with the challenges in identifying genetic, epigenetic, and transcriptomic biomarkers. The infectious disease section describes the current clinical applications of molecular diagnostics for the detection of viral, bacterial, and fu
Member of
Cataloging source
LGG
Dewey number
616.07/56
Index
no index present
LC call number
RB43.7
LC item number
.M65 2014
Literary form
non fiction
Nature of contents
dictionaries
http://library.link/vocab/relatedWorkOrContributorName
Huggett, Jim F.
http://library.link/vocab/subjectName
  • Molecular diagnosis
  • Cancer
  • Communicable diseases
  • Molecular Diagnostic Techniques
  • Nucleic Acid Amplification Techniques
  • Biomarkers
  • Neoplasms
  • Communicable Diseases
  • HEALTH & FITNESS
  • MEDICAL
  • MEDICAL
  • MEDICAL
  • MEDICAL
  • Cancer
  • Molecular diagnosis
Label
Molecular diagnostics : current research and applications, edited by Jim F. Huggett and Justin O'Grady
Instantiates
Publication
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • Contributors; Current books of interest; Foreword; Biographies; 1: Molecular Diagnostics: An Introduction; Part I: Molecular Diagnostics in Cancer: Research and Development of Biomarkers; 2: Transcriptome-based Biomarkers: A Road Map Exemplified for Peripheral Blood-based Biomarker Discovery, Development and Clinical Use; Introduction; Defining biomarker classes as a prerequisite for successful biomarker development; Focus on peripheral blood-based biomarkers as an example; Blood transcriptomics started in leukaemia research
  • Is there a role for blood transcriptomics in other diseases?Is there a role of blood transcriptomics for early detection of disease?; General guidance towards successful biomarker development; Importance of technical and organizational aspects during biomarker development; Requirements for bioinformatics analysis during biomarker development; The next decade of blood transcriptomics; 3: Development of Methylation Biomarkers for Clinical Applications and Methylation-sensitive High-resolution Melting Technology; DNA methylation; Methylation-based in vitro diagnostic tests
  • Fields of applications of in vitro diagnostic testsChallenges of methylation biomarker development process; Methylation biomarker development workflow; PCR amplification and melting analyses in methylation studies; Development of methylation-sensitive high-resolution melting (MS-HRM); Characteristics of the MS-HRM protocol; Final remarks; 4: Genetic and Epigenetic Biomarkers of Colorectal Cancer ; Introduction; Biomarkers; Biomarker location; Practical limitations; Conclusions and outlook; Part II: Molecular Diagnostics of Infectious Diseases: Past, Present and Future
  • 5: Molecular Diagnosis in Medical Microbiology: The Horizon Draws NearIntroduction; Enhancing diagnosis; Molecular typing in control of infection; Molecular tools in screening/high-throughput analysis; Considerations in selecting a molecular tool; Conclusion; 6: Viral Diagnostics and qPCR-based Methodologies; Introduction; PCR-based methods; Non-PCR-based methods; Perspectives; Validation/standardization/harmonization; Conclusions; 7: XMRV: A Cautionary Tale; Introduction; Discovery of XMRV; Reports of XMRV in prostate cancer and chronic fatigue syndrome
  • Mounting negative evidence ignites XMRV controversyHuman pathogen or laboratory contaminant?; The recombinant origin of XMRV; Dénouement and conclusions; Note added in proof; 8: Ancient DNA and the Fingerprints of Disease: Retrieving Human Pathogen Genomic Sequences from Archaeological Remains Using Real-time Quantitative Polymerase Chain Reaction; Introduction; aDNA breakdown after deposition; Why study aDNA and what can it tell us?; Sampling and measures to avoid cross-contamination; PCR; Validation of PCR findings; Conclusions; Part III: From Bench to Bedside
Control code
876880344
Dimensions
unknown
Extent
1 online resource
Form of item
online
Isbn
9781908230645
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Sound
unknown sound
Specific material designation
remote
System control number
(OCoLC)876880344
Label
Molecular diagnostics : current research and applications, edited by Jim F. Huggett and Justin O'Grady
Publication
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • Contributors; Current books of interest; Foreword; Biographies; 1: Molecular Diagnostics: An Introduction; Part I: Molecular Diagnostics in Cancer: Research and Development of Biomarkers; 2: Transcriptome-based Biomarkers: A Road Map Exemplified for Peripheral Blood-based Biomarker Discovery, Development and Clinical Use; Introduction; Defining biomarker classes as a prerequisite for successful biomarker development; Focus on peripheral blood-based biomarkers as an example; Blood transcriptomics started in leukaemia research
  • Is there a role for blood transcriptomics in other diseases?Is there a role of blood transcriptomics for early detection of disease?; General guidance towards successful biomarker development; Importance of technical and organizational aspects during biomarker development; Requirements for bioinformatics analysis during biomarker development; The next decade of blood transcriptomics; 3: Development of Methylation Biomarkers for Clinical Applications and Methylation-sensitive High-resolution Melting Technology; DNA methylation; Methylation-based in vitro diagnostic tests
  • Fields of applications of in vitro diagnostic testsChallenges of methylation biomarker development process; Methylation biomarker development workflow; PCR amplification and melting analyses in methylation studies; Development of methylation-sensitive high-resolution melting (MS-HRM); Characteristics of the MS-HRM protocol; Final remarks; 4: Genetic and Epigenetic Biomarkers of Colorectal Cancer ; Introduction; Biomarkers; Biomarker location; Practical limitations; Conclusions and outlook; Part II: Molecular Diagnostics of Infectious Diseases: Past, Present and Future
  • 5: Molecular Diagnosis in Medical Microbiology: The Horizon Draws NearIntroduction; Enhancing diagnosis; Molecular typing in control of infection; Molecular tools in screening/high-throughput analysis; Considerations in selecting a molecular tool; Conclusion; 6: Viral Diagnostics and qPCR-based Methodologies; Introduction; PCR-based methods; Non-PCR-based methods; Perspectives; Validation/standardization/harmonization; Conclusions; 7: XMRV: A Cautionary Tale; Introduction; Discovery of XMRV; Reports of XMRV in prostate cancer and chronic fatigue syndrome
  • Mounting negative evidence ignites XMRV controversyHuman pathogen or laboratory contaminant?; The recombinant origin of XMRV; Dénouement and conclusions; Note added in proof; 8: Ancient DNA and the Fingerprints of Disease: Retrieving Human Pathogen Genomic Sequences from Archaeological Remains Using Real-time Quantitative Polymerase Chain Reaction; Introduction; aDNA breakdown after deposition; Why study aDNA and what can it tell us?; Sampling and measures to avoid cross-contamination; PCR; Validation of PCR findings; Conclusions; Part III: From Bench to Bedside
Control code
876880344
Dimensions
unknown
Extent
1 online resource
Form of item
online
Isbn
9781908230645
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Sound
unknown sound
Specific material designation
remote
System control number
(OCoLC)876880344

Library Locations

    • Curtis Laws Wilson LibraryBorrow it
      400 West 14th Street, Rolla, MO, 65409, US
      37.955220 -91.772210
Processing Feedback ...