The Resource New frontiers in chemical biology : enabling drug discovery, [edited by] Mark Bunnage, David Thurston, David Fox
New frontiers in chemical biology : enabling drug discovery, [edited by] Mark Bunnage, David Thurston, David Fox
Resource Information
The item New frontiers in chemical biology : enabling drug discovery, [edited by] Mark Bunnage, David Thurston, David Fox represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in Missouri University of Science & Technology Library.This item is available to borrow from 1 library branch.
Resource Information
The item New frontiers in chemical biology : enabling drug discovery, [edited by] Mark Bunnage, David Thurston, David Fox represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in Missouri University of Science & Technology Library.
This item is available to borrow from 1 library branch.
- Extent
- 1 online resource
- Contents
-
- The chemical genetic approach : the interrogation of biological mechanisms with small molecule probes / Martin Fisher and Adam Nelson
- Applications for activity-based probes in drug discovery / L.E. Edgington and M. Bogyo
- Targeted intracellular protein degradation as a potential therapeutic strategy / A.R. Schneekloth and C.M. Crews
- Chemical biology of stem cell modulation / Stephen G. Davies and Angela J. Russell
- Chemical biology of histone modifications / Nathan R. Rose, Christopher J. Schofield and Tom D. Heightman
- Chemologics / Lyn H. Jones
- Antibody-drug conjugates in oncology / Philip R. Hamann and Russell G. Dushin
- Drug discovery by DNA-encoded libraries / Yizhou Li, Zheng Zhu and Xiaoyu Li
- Isbn
- 9781849732178
- Label
- New frontiers in chemical biology : enabling drug discovery
- Title
- New frontiers in chemical biology
- Title remainder
- enabling drug discovery
- Statement of responsibility
- [edited by] Mark Bunnage, David Thurston, David Fox
- Subject
-
- Structure-Activity Relationship
- Biochemical Phenomena
- Biological Science Disciplines
- Chemical Actions and Uses
- Chemical Phenomena
- Chemistry
- Chemistry, Pharmaceutical
- Drug Discovery
- Drugs -- Design
- Drugs -- Design
- Electronic books
- Genetic Phenomena
- Genetic Structures
- Investigative Techniques
- Laboratory Chemicals
- MEDICAL -- Drug Guides
- MEDICAL -- Nursing | Pharmacology
- MEDICAL -- Pharmacology
- MEDICAL -- Pharmacy
- Natural Science Disciplines
- Pharmaceutical chemistry
- Pharmaceutical chemistry
- Pharmacological Phenomena
- Pharmacology
- Phenomena and Processes
- Physiological Phenomena
- Small Molecule Libraries
- Specialty Uses of Chemicals
- Language
- eng
- Summary
- Annotation
- Cataloging source
- UKRSC
- Dewey number
- 615/.19
- Index
- index present
- Language note
- English
- LC call number
- RS420
- LC item number
- .N49 2010
- Literary form
- non fiction
- Nature of contents
-
- dictionaries
- bibliography
- http://library.link/vocab/relatedWorkOrContributorName
-
- Bunnage, Mark E
- Thurston, David E
- Fox, David
- Series statement
- RSC drug discovery
- Series volume
- 5
- http://library.link/vocab/subjectName
-
- Drugs
- Pharmaceutical chemistry
- Laboratory Chemicals
- Chemistry, Pharmaceutical
- Genetic Phenomena
- Investigative Techniques
- Biochemical Phenomena
- Pharmacological Phenomena
- Phenomena and Processes
- Specialty Uses of Chemicals
- Pharmacology
- Chemistry
- Chemical Phenomena
- Physiological Phenomena
- Chemical Actions and Uses
- Natural Science Disciplines
- Biological Science Disciplines
- Structure-Activity Relationship
- Small Molecule Libraries
- Drug Discovery
- Genetic Structures
- MEDICAL
- MEDICAL
- MEDICAL
- MEDICAL
- Drugs
- Pharmaceutical chemistry
- Summary expansion
- Despite ever-increasing investment in biomedical research, there has been a significant decline in the number of new drug approvals in recent years. In an effort to improve productivity, the drug discovery community has increasingly looked to biotherapeutics such as antibodies, vaccines, nucleic acids, and peptides. Chemical biology is an emerging field at the interface between chemistry and biology. It utilises the tools and techniques of chemical synthesis to study and influence biological systems. Recent developments in this area have great potential in addressing the productivity challenges expressed above. For example, chemical biology studies have already led to the identification of novel targets with exciting therapeutic potential and it is clear that the field will prove a key enabler of target discovery in the future. Moreover, the precise synthetic manipulation of biological molecules involved in many chemical biology approaches is now fuelling a new wave of chemically-modified biologics, 'chemologics', with unique properties. In these, and many other ways, chemical biology is a key discipline within 21st century drug discovery and the purpose of this book is to highlight the most important developments. It provides a valuable resource for scientists in academia and industry who are looking to build their knowledge of this hot topic. The individual chapters cover crucial areas including chemical proteomics, chemical genetics, post-translational modifications, epigenetics, RNA interference, PROTACS, antibody-drug conjugates, and chemologics
- Label
- New frontiers in chemical biology : enabling drug discovery, [edited by] Mark Bunnage, David Thurston, David Fox
- Bibliography note
- Includes bibliographical references and index
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Color
- multicolored
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Contents
- The chemical genetic approach : the interrogation of biological mechanisms with small molecule probes / Martin Fisher and Adam Nelson -- Applications for activity-based probes in drug discovery / L.E. Edgington and M. Bogyo -- Targeted intracellular protein degradation as a potential therapeutic strategy / A.R. Schneekloth and C.M. Crews -- Chemical biology of stem cell modulation / Stephen G. Davies and Angela J. Russell -- Chemical biology of histone modifications / Nathan R. Rose, Christopher J. Schofield and Tom D. Heightman -- Chemologics / Lyn H. Jones -- Antibody-drug conjugates in oncology / Philip R. Hamann and Russell G. Dushin -- Drug discovery by DNA-encoded libraries / Yizhou Li, Zheng Zhu and Xiaoyu Li
- Control code
- 642690095
- Dimensions
- unknown
- Extent
- 1 online resource
- Form of item
- online
- Isbn
- 9781849732178
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- Other control number
- 10.1039/9781849732178
- http://library.link/vocab/ext/overdrive/overdriveId
- t3317
- Specific material designation
- remote
- System control number
- (OCoLC)642690095
- Label
- New frontiers in chemical biology : enabling drug discovery, [edited by] Mark Bunnage, David Thurston, David Fox
- Bibliography note
- Includes bibliographical references and index
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Color
- multicolored
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Contents
- The chemical genetic approach : the interrogation of biological mechanisms with small molecule probes / Martin Fisher and Adam Nelson -- Applications for activity-based probes in drug discovery / L.E. Edgington and M. Bogyo -- Targeted intracellular protein degradation as a potential therapeutic strategy / A.R. Schneekloth and C.M. Crews -- Chemical biology of stem cell modulation / Stephen G. Davies and Angela J. Russell -- Chemical biology of histone modifications / Nathan R. Rose, Christopher J. Schofield and Tom D. Heightman -- Chemologics / Lyn H. Jones -- Antibody-drug conjugates in oncology / Philip R. Hamann and Russell G. Dushin -- Drug discovery by DNA-encoded libraries / Yizhou Li, Zheng Zhu and Xiaoyu Li
- Control code
- 642690095
- Dimensions
- unknown
- Extent
- 1 online resource
- Form of item
- online
- Isbn
- 9781849732178
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- Other control number
- 10.1039/9781849732178
- http://library.link/vocab/ext/overdrive/overdriveId
- t3317
- Specific material designation
- remote
- System control number
- (OCoLC)642690095
Subject
- Structure-Activity Relationship
- Biochemical Phenomena
- Biological Science Disciplines
- Chemical Actions and Uses
- Chemical Phenomena
- Chemistry
- Chemistry, Pharmaceutical
- Drug Discovery
- Drugs -- Design
- Drugs -- Design
- Electronic books
- Genetic Phenomena
- Genetic Structures
- Investigative Techniques
- Laboratory Chemicals
- MEDICAL -- Drug Guides
- MEDICAL -- Nursing | Pharmacology
- MEDICAL -- Pharmacology
- MEDICAL -- Pharmacy
- Natural Science Disciplines
- Pharmaceutical chemistry
- Pharmaceutical chemistry
- Pharmacological Phenomena
- Pharmacology
- Phenomena and Processes
- Physiological Phenomena
- Small Molecule Libraries
- Specialty Uses of Chemicals
Genre
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<div class="citation" vocab="http://schema.org/"><i class="fa fa-external-link-square fa-fw"></i> Data from <span resource="http://link.library.mst.edu/portal/New-frontiers-in-chemical-biology--enabling-drug/7FyEa5-SNWs/" typeof="Book http://bibfra.me/vocab/lite/Item"><span property="name http://bibfra.me/vocab/lite/label"><a href="http://link.library.mst.edu/portal/New-frontiers-in-chemical-biology--enabling-drug/7FyEa5-SNWs/">New frontiers in chemical biology : enabling drug discovery, [edited by] Mark Bunnage, David Thurston, David Fox</a></span> - <span property="potentialAction" typeOf="OrganizeAction"><span property="agent" typeof="LibrarySystem http://library.link/vocab/LibrarySystem" resource="http://link.library.mst.edu/"><span property="name http://bibfra.me/vocab/lite/label"><a property="url" href="http://link.library.mst.edu/">Missouri University of Science & Technology Library</a></span></span></span></span></div>
