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The Resource Profiles of drug substances, excipients and related methodology, Volume 39, edited by Harry G. Brittain

Profiles of drug substances, excipients and related methodology, Volume 39, edited by Harry G. Brittain

Label
Profiles of drug substances, excipients and related methodology, Volume 39
Title
Profiles of drug substances, excipients and related methodology
Title number
Volume 39
Statement of responsibility
edited by Harry G. Brittain
Contributor
Editor
Subject
Language
eng
Summary
Volumes in this widely revered series present comprehensive reviews of drug substances and additional materials, with critical review chapters that summarize information related to the characterization of drug substances and excipients. This organizational structure meets the needs of the pharmaceutical community and allows for the development of a timely vehicle for publishing review materials on this topic. The scope of the Profiles series encompasses review articles and database compilations that fall within one of the following six broad categories: Physical profiles of drug substances and excipients; Analytical profiles of drug substances and excipients; Drug metabolism and pharmacokinetic profiles of drug substances and excipients; Methodology related to the characterization of drug substances and excipients; Methods of chemical synthesis; and Reviews of the uses and applications for individual drug substances, classes of drug substances, or excipients
Cataloging source
E7B
Dewey number
615.1
Illustrations
illustrations
Index
index present
LC call number
RS189
LC item number
.P764 2014eb
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
http://library.link/vocab/relatedWorkOrContributorName
Brittain, H. G.
http://library.link/vocab/subjectName
  • Drugs
  • Excipients
  • Pharmaceutical chemistry
  • MEDICAL
  • Drugs
  • Pharmaceutical chemistry
Label
Profiles of drug substances, excipients and related methodology, Volume 39, edited by Harry G. Brittain
Instantiates
Publication
Copyright
Bibliography note
Includes bibliographical references at the end of each chapters and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • Front Cover; Profiles of Drug Substances, Excipients, and Related Methodology; Copyright; Contents; Preface to Volume 39; Chapter One: Azithromycin; Background; 1. Description; 1.1. Nomenclature; 1.1.1. Systematic chemical names [2-5]; 1.1.2. Nonproprietary names; 1.1.3. Proprietary names [3,7,8]; 1.2. Formulae[2,3]; 1.2.1. Empirical formula, molecular weight, CAS number; 1.2.2. Structural formula; 1.3. Elemental analysis; 1.4. Appearance [2]; 2. Methods of Preparation of Azithromycin; 3. Physical Characteristics; 3.1. Specific optical rotation [5,21]; 3.2. Ionization constant [22]
  • 3.3. Solubility characteristics [21]3.4. Partition coefficient; 3.5. Particle morphology; 3.6. Crystallographic properties; 3.6.1. Single crystal structure; 3.6.2. X-ray powder diffraction pattern [28]; 3.7. Hygroscopicity; 3.8. Thermal methods of analysis; 3.8.1. Melting behavior; 3.8.2. Differential scanning calorimetry [25]; 3.8.3. Thermogravimetric analysis; 3.8.4. Karl Fischer titration (KFT) [25]; 3.8.5. Boiling point, enthalpy of vapor, flash point, and vapor pressure; 3.9. Spectroscopy; 3.9.1. UV/Vis spectroscopy; 3.9.2. Vibrational spectroscopy [32]
  • 3.9.3. Nuclear magnetic resonance spectrometry [33]3.9.3.1. 1H NMR spectrum [33]; 3.9.3.2. 13C NMR spectrum [33]; 3.10. Mass spectrometry [34]; 4. Methods of Analysis; 4.1. Compendial methods of analysis; 4.1.1. Identification; 4.1.1.1. IR spectrum of Azithromycin; 4.1.1.2. HPLC drug chromatogram; 4.1.2. Impurity Analysis [47]; 4.1.3. Other tests; 4.1.3.1. Water [47]; 4.1.3.2. Sulphated ash [47]; 4.1.4. Assay method [47]; 4.1.4.1. Liquid chromatography; 4.2. Electrochemical methods of analysis; 4.2.1. Voltammetry; 4.2.2. Coulometry; 4.3. Spectroscopic methods of analysis
  • 4.3.1. Spectrophotometry4.3.2. Spectrofluorimetry; 4.3.3. Colorimetry; 4.4. Chromatographic methods of analysis; 4.4.1. Electrophoresis; 4.4.2. Thin-layer chromatography; 4.4.3. High-performance liquid chromatography; 4.5. Determination in body fluids and tissues; 5. Stability; 6. Clinical Applications; 6.1. An overview; 6.2. Antimicrobial spectrum susceptibility; 6.3. Mechanism of action; 6.4. Resistance to macrolides; 6.5. Actions other than antimicrobial effects; 6.6. Clinical uses and dosing; 6.7. ADME profile; 6.8. Side effects; 6.9. Drug interactions; References; Chapter Two: Cefdinir
  • 1. Description1.1. Nomenclature; 1.1.1. Systematic chemical names; 1.1.2. Non-proprietary names; 1.1.3. Proprietary names; 1.2. Formulae; 1.2.1. Empirical formula, molecular weight, and CAS number; 1.2.2. Structural formula; 1.3. Elemental analysis; 1.4. Appearance; 2. Uses and Applications; 3. Methods of Preparation; 4. Physical Characteristics; 4.1. Ionization constant; 4.2. Solubility; 4.3. X-ray powder diffraction; 4.4. Thermal methods of analysis; 4.4.1. Melting point; 4.4.2. Differential scanning calorimetry; 5. Spectral Properties; 5.1. Ultraviolet spectroscopy
Control code
880456154
Dimensions
unknown
Edition
First edition.
Extent
1 online resource (562 pages)
Form of item
online
Isbn
9780128004012
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations
Specific material designation
remote
System control number
(OCoLC)880456154
Label
Profiles of drug substances, excipients and related methodology, Volume 39, edited by Harry G. Brittain
Publication
Copyright
Bibliography note
Includes bibliographical references at the end of each chapters and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • Front Cover; Profiles of Drug Substances, Excipients, and Related Methodology; Copyright; Contents; Preface to Volume 39; Chapter One: Azithromycin; Background; 1. Description; 1.1. Nomenclature; 1.1.1. Systematic chemical names [2-5]; 1.1.2. Nonproprietary names; 1.1.3. Proprietary names [3,7,8]; 1.2. Formulae[2,3]; 1.2.1. Empirical formula, molecular weight, CAS number; 1.2.2. Structural formula; 1.3. Elemental analysis; 1.4. Appearance [2]; 2. Methods of Preparation of Azithromycin; 3. Physical Characteristics; 3.1. Specific optical rotation [5,21]; 3.2. Ionization constant [22]
  • 3.3. Solubility characteristics [21]3.4. Partition coefficient; 3.5. Particle morphology; 3.6. Crystallographic properties; 3.6.1. Single crystal structure; 3.6.2. X-ray powder diffraction pattern [28]; 3.7. Hygroscopicity; 3.8. Thermal methods of analysis; 3.8.1. Melting behavior; 3.8.2. Differential scanning calorimetry [25]; 3.8.3. Thermogravimetric analysis; 3.8.4. Karl Fischer titration (KFT) [25]; 3.8.5. Boiling point, enthalpy of vapor, flash point, and vapor pressure; 3.9. Spectroscopy; 3.9.1. UV/Vis spectroscopy; 3.9.2. Vibrational spectroscopy [32]
  • 3.9.3. Nuclear magnetic resonance spectrometry [33]3.9.3.1. 1H NMR spectrum [33]; 3.9.3.2. 13C NMR spectrum [33]; 3.10. Mass spectrometry [34]; 4. Methods of Analysis; 4.1. Compendial methods of analysis; 4.1.1. Identification; 4.1.1.1. IR spectrum of Azithromycin; 4.1.1.2. HPLC drug chromatogram; 4.1.2. Impurity Analysis [47]; 4.1.3. Other tests; 4.1.3.1. Water [47]; 4.1.3.2. Sulphated ash [47]; 4.1.4. Assay method [47]; 4.1.4.1. Liquid chromatography; 4.2. Electrochemical methods of analysis; 4.2.1. Voltammetry; 4.2.2. Coulometry; 4.3. Spectroscopic methods of analysis
  • 4.3.1. Spectrophotometry4.3.2. Spectrofluorimetry; 4.3.3. Colorimetry; 4.4. Chromatographic methods of analysis; 4.4.1. Electrophoresis; 4.4.2. Thin-layer chromatography; 4.4.3. High-performance liquid chromatography; 4.5. Determination in body fluids and tissues; 5. Stability; 6. Clinical Applications; 6.1. An overview; 6.2. Antimicrobial spectrum susceptibility; 6.3. Mechanism of action; 6.4. Resistance to macrolides; 6.5. Actions other than antimicrobial effects; 6.6. Clinical uses and dosing; 6.7. ADME profile; 6.8. Side effects; 6.9. Drug interactions; References; Chapter Two: Cefdinir
  • 1. Description1.1. Nomenclature; 1.1.1. Systematic chemical names; 1.1.2. Non-proprietary names; 1.1.3. Proprietary names; 1.2. Formulae; 1.2.1. Empirical formula, molecular weight, and CAS number; 1.2.2. Structural formula; 1.3. Elemental analysis; 1.4. Appearance; 2. Uses and Applications; 3. Methods of Preparation; 4. Physical Characteristics; 4.1. Ionization constant; 4.2. Solubility; 4.3. X-ray powder diffraction; 4.4. Thermal methods of analysis; 4.4.1. Melting point; 4.4.2. Differential scanning calorimetry; 5. Spectral Properties; 5.1. Ultraviolet spectroscopy
Control code
880456154
Dimensions
unknown
Edition
First edition.
Extent
1 online resource (562 pages)
Form of item
online
Isbn
9780128004012
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations
Specific material designation
remote
System control number
(OCoLC)880456154

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