The Resource Protein-protein interactions in drug discovery, edited by Alexander Dömling
Protein-protein interactions in drug discovery, edited by Alexander Dömling
Resource Information
The item Protein-protein interactions in drug discovery, edited by Alexander Dömling represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in Missouri University of Science & Technology Library.This item is available to borrow from 1 library branch.
Resource Information
The item Protein-protein interactions in drug discovery, edited by Alexander Dömling represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in Missouri University of Science & Technology Library.
This item is available to borrow from 1 library branch.
- Summary
- Treating protein-protein interactions as a novel and highly promising class of drug targets, this volume introduces the underlying strategies step by step, from the biology of PPIs to biophysical and computational methods for their investigation. The main part of the book describes examples of protein targets for which small molecule modulators have been developed, covering such diverse fields as cancer, autoimmune disorders and infectious diseases. Tailor-made for the practicing medicinal chemist, this ready reference includes a wide selection of case studies taken straight from the devel
- Language
- eng
- Extent
- 1 online resource (xxi, 314 pages)
- Contents
-
- Protein-protein interactions: an vverview / Christian Ottman
- Prediction of intra- and interspecies protein-protein interactions facilitating systems biology studies / Sylvia Schleker, Seshan Ananthasubramanian, Judith Klein-Seetharaman, Madhavi K Ganapathiraju
- Modulators of protein-protein interactions: importance of three-dimensionality / David C Fry, Sung-Sau So
- A leap into the chemical space of protein-protein interaction inhibitors / Bruno O Villoutreix, C Labbé, David Lagorce, Guillaume Laconde, Olivier Sperandio
- Interactive technologies for leveraging the known chemistry of anchor residues to disrupt protein interactions / Carlos J Camacho, David R Koes, Alexander S Dömling
- SH3 domains as drug targets / James Luccarelli, Sam Thompson, Andrew D Hamilton
- p53/MDM2 antagonists: towards nongenotoxic anticancer treatments / Kareem Khoury, Tad A Holak, Alexander Dömling
- Inhibition of LFA-1/ICAM interaction for the treatment of autoimmune diseases / Kevin M Guckian, Daniel M Scott
- The PIF pocket of AGC kinases: a target site for allosteric modulators and protein-protein interaction inhibitors / Matthias Engel
- Retosiban and epelsiban: potent and selective orally available oxytocin antagonists / Alan D Borthwick, John Liddle
- Peptidic inhibitors of protein-protein interactions for cell adhesion receptors: RGD peptides and beyond / Carlos Mas-Moruno, Horst Kessler
- REPLACE strategy for generating non-ATP-competitive inhibitors of cell cycle protein kinases / Campbell McInnes
- Index
- Isbn
- 9783527648238
- Label
- Protein-protein interactions in drug discovery
- Title
- Protein-protein interactions in drug discovery
- Statement of responsibility
- edited by Alexander Dömling
- Subject
-
- Proteins -- Inhibitors
- Carrier Proteins
- Drug Discovery
- Electronic book
- Electronic books
- Electronic books
- MEDICAL -- Drug Guides
- MEDICAL -- Nursing | Pharmacology
- MEDICAL -- Pharmacology
- MEDICAL -- Pharmacy
- Protein Interaction Domains and Motifs
- Protein binding
- Protein binding
- Protein-protein interactions
- Protein-protein interactions
- Language
- eng
- Summary
- Treating protein-protein interactions as a novel and highly promising class of drug targets, this volume introduces the underlying strategies step by step, from the biology of PPIs to biophysical and computational methods for their investigation. The main part of the book describes examples of protein targets for which small molecule modulators have been developed, covering such diverse fields as cancer, autoimmune disorders and infectious diseases. Tailor-made for the practicing medicinal chemist, this ready reference includes a wide selection of case studies taken straight from the devel
- Cataloging source
- E7B
- Dewey number
- 615.19
- Illustrations
- illustrations
- Index
- index present
- LC call number
- QP551.5
- LC item number
- .P76 2013eb
- Literary form
- non fiction
- Nature of contents
-
- dictionaries
- bibliography
- NLM call number
-
- W1
- QU 55
- NLM item number
- ME961EH v.56 2013
- http://library.link/vocab/relatedWorkOrContributorName
- Dömling, Alexander
- Series statement
- Methods and principles in medicinal chemistry
- Series volume
- v. 56
- http://library.link/vocab/subjectName
-
- Protein-protein interactions
- Protein binding
- Proteins
- Carrier Proteins
- Drug Discovery
- Protein Interaction Domains and Motifs
- MEDICAL
- MEDICAL
- MEDICAL
- MEDICAL
- Protein binding
- Protein-protein interactions
- Label
- Protein-protein interactions in drug discovery, edited by Alexander Dömling
- Bibliography note
- Includes bibliographical references and index
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Color
- multicolored
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Contents
- Protein-protein interactions: an vverview / Christian Ottman -- Prediction of intra- and interspecies protein-protein interactions facilitating systems biology studies / Sylvia Schleker, Seshan Ananthasubramanian, Judith Klein-Seetharaman, Madhavi K Ganapathiraju -- Modulators of protein-protein interactions: importance of three-dimensionality / David C Fry, Sung-Sau So -- A leap into the chemical space of protein-protein interaction inhibitors / Bruno O Villoutreix, C Labbé, David Lagorce, Guillaume Laconde, Olivier Sperandio -- Interactive technologies for leveraging the known chemistry of anchor residues to disrupt protein interactions / Carlos J Camacho, David R Koes, Alexander S Dömling -- SH3 domains as drug targets / James Luccarelli, Sam Thompson, Andrew D Hamilton -- p53/MDM2 antagonists: towards nongenotoxic anticancer treatments / Kareem Khoury, Tad A Holak, Alexander Dömling -- Inhibition of LFA-1/ICAM interaction for the treatment of autoimmune diseases / Kevin M Guckian, Daniel M Scott -- The PIF pocket of AGC kinases: a target site for allosteric modulators and protein-protein interaction inhibitors / Matthias Engel -- Retosiban and epelsiban: potent and selective orally available oxytocin antagonists / Alan D Borthwick, John Liddle -- Peptidic inhibitors of protein-protein interactions for cell adhesion receptors: RGD peptides and beyond / Carlos Mas-Moruno, Horst Kessler -- REPLACE strategy for generating non-ATP-competitive inhibitors of cell cycle protein kinases / Campbell McInnes -- Index
- Control code
- 828743731
- Dimensions
- unknown
- Extent
- 1 online resource (xxi, 314 pages)
- Form of item
- online
- Isbn
- 9783527648238
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- Other physical details
- illustrations
- Specific material designation
- remote
- System control number
- (OCoLC)828743731
- Label
- Protein-protein interactions in drug discovery, edited by Alexander Dömling
- Bibliography note
- Includes bibliographical references and index
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Color
- multicolored
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Contents
- Protein-protein interactions: an vverview / Christian Ottman -- Prediction of intra- and interspecies protein-protein interactions facilitating systems biology studies / Sylvia Schleker, Seshan Ananthasubramanian, Judith Klein-Seetharaman, Madhavi K Ganapathiraju -- Modulators of protein-protein interactions: importance of three-dimensionality / David C Fry, Sung-Sau So -- A leap into the chemical space of protein-protein interaction inhibitors / Bruno O Villoutreix, C Labbé, David Lagorce, Guillaume Laconde, Olivier Sperandio -- Interactive technologies for leveraging the known chemistry of anchor residues to disrupt protein interactions / Carlos J Camacho, David R Koes, Alexander S Dömling -- SH3 domains as drug targets / James Luccarelli, Sam Thompson, Andrew D Hamilton -- p53/MDM2 antagonists: towards nongenotoxic anticancer treatments / Kareem Khoury, Tad A Holak, Alexander Dömling -- Inhibition of LFA-1/ICAM interaction for the treatment of autoimmune diseases / Kevin M Guckian, Daniel M Scott -- The PIF pocket of AGC kinases: a target site for allosteric modulators and protein-protein interaction inhibitors / Matthias Engel -- Retosiban and epelsiban: potent and selective orally available oxytocin antagonists / Alan D Borthwick, John Liddle -- Peptidic inhibitors of protein-protein interactions for cell adhesion receptors: RGD peptides and beyond / Carlos Mas-Moruno, Horst Kessler -- REPLACE strategy for generating non-ATP-competitive inhibitors of cell cycle protein kinases / Campbell McInnes -- Index
- Control code
- 828743731
- Dimensions
- unknown
- Extent
- 1 online resource (xxi, 314 pages)
- Form of item
- online
- Isbn
- 9783527648238
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- Other physical details
- illustrations
- Specific material designation
- remote
- System control number
- (OCoLC)828743731
Subject
- Proteins -- Inhibitors
- Carrier Proteins
- Drug Discovery
- Electronic book
- Electronic books
- Electronic books
- MEDICAL -- Drug Guides
- MEDICAL -- Nursing | Pharmacology
- MEDICAL -- Pharmacology
- MEDICAL -- Pharmacy
- Protein Interaction Domains and Motifs
- Protein binding
- Protein binding
- Protein-protein interactions
- Protein-protein interactions
Genre
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<div class="citation" vocab="http://schema.org/"><i class="fa fa-external-link-square fa-fw"></i> Data from <span resource="http://link.library.mst.edu/portal/Protein-protein-interactions-in-drug-discovery/sflPYwtyYUY/" typeof="Book http://bibfra.me/vocab/lite/Item"><span property="name http://bibfra.me/vocab/lite/label"><a href="http://link.library.mst.edu/portal/Protein-protein-interactions-in-drug-discovery/sflPYwtyYUY/">Protein-protein interactions in drug discovery, edited by Alexander Dömling</a></span> - <span property="potentialAction" typeOf="OrganizeAction"><span property="agent" typeof="LibrarySystem http://library.link/vocab/LibrarySystem" resource="http://link.library.mst.edu/"><span property="name http://bibfra.me/vocab/lite/label"><a property="url" href="http://link.library.mst.edu/">Missouri University of Science & Technology Library</a></span></span></span></span></div>
