Coverart for item
The Resource Structure to function of G protein-gated inwardly rectifying (GIRK) channels, volume editors, Paul A. Slesinger, Kevin Wickman

Structure to function of G protein-gated inwardly rectifying (GIRK) channels, volume editors, Paul A. Slesinger, Kevin Wickman

Label
Structure to function of G protein-gated inwardly rectifying (GIRK) channels
Title
Structure to function of G protein-gated inwardly rectifying (GIRK) channels
Statement of responsibility
volume editors, Paul A. Slesinger, Kevin Wickman
Contributor
Editor
Subject
Language
eng
Summary
Annotation
Member of
Cataloging source
NLE
Dewey number
572.3
Index
index present
LC call number
QP552.G16
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
QU 55.7
http://library.link/vocab/relatedWorkOrContributorName
  • Slesinger, Paul A.
  • Wickman, Kevin D.
Series statement
International Review of Neurobiology
Series volume
v. Volume 123
http://library.link/vocab/subjectName
  • Potassium channels
  • G proteins
  • Substance abuse
  • Receptors, G-Protein-Coupled
  • Potassium Channels
  • SCIENCE
  • Substance abuse
  • Potassium channels
Summary expansion
A comprehensive overview of state-of-the-art research into GIRK potassium channels. It reviews current knowledge and understanding, providing a starting point for researchers and practitioners entering the field
Label
Structure to function of G protein-gated inwardly rectifying (GIRK) channels, volume editors, Paul A. Slesinger, Kevin Wickman
Instantiates
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • Title page -- Table of Contents -- Copyright -- Contributors -- Preface -- Chapter One: Unifying Mechanism of Controlling Kir3 Channel Activity by G Proteins and Phosphoinositides -- Abstract -- 1 Introduction -- 2 Regulation of KACh by G Proteins -- 3 Molecular Constituents of Kir3 Channels and Physiological Roles -- 4 Dependence of KACh Channel Activity on PIPs -- 5 Physiological Significance of Distinct Membrane-Delimited Signaling Mechanisms -- 6 Molecular Mechanism of PIP2 Control of Kir Channel Gating
  • 7 Posttranslational Modification Can Control Activity Through Changes in Channelâ€"PIP2 Interactions8 The Kir3 Channel Site of GÎ2Î3 Action -- Chapter Two: The Roles of GÎ2Î3 and Gα in Gating and Regulation of GIRK Channels -- Abstract -- 1 Introduction -- 2 Interaction of Gα and GÎ2Î3 With GIRK -- 3 Roles of GÎ2Î3 and Gα in GIRK's Evoked and Basal Activity -- 4 Basal Activity of GIRKs -- 5 Multimolecular Signaling Complex and the Mechanism of GIRK Activation -- Acknowledgments -- Chapter Three: RGS Redundancy and Implications in GPCRâ€"GIRK Signaling
  • 2 Selectivity and Permeation3 Rectification -- 4 Gating -- 5 Conclusions -- Acknowledgments -- Chapter Five: Localization and Targeting of GIRK Channels in Mammalian Central Neurons -- Abstract -- 1 Introduction -- 2 Molecular Organization and Heterogeneity of GIRK Channels -- 3 Neuroanatomical Approaches to the Study of GIRK Channel Distribution -- 4 Regional Distribution of GIRK Channel Subunits in the CNS -- 5 Cellular Distribution of GIRK Channel Subunits -- 6 Subcellular Distribution of GIRK Channel Subunits
  • 7 Developmental Aspects of GIRK Channel Distribution8 Conclusions and Future Perspectives -- Acknowledgments -- Chapter Six: GIRK Channel Plasticity and Implications for Drug Addiction -- Abstract -- 1 Introduction -- 2 GIRK Channels in the Mesocorticolimbic System -- 3 Drug-Dependent Plasticity of GIRK Channel-Dependent Signaling -- 4 Mechanisms Underlying the Plasticity of GIRK Channel-Dependent Signaling -- 5 Concluding Thoughts and Future Directions -- Acknowledgments -- Chapter Seven: GIRK Channels: A Potential Link Between Learning and Addiction -- Abstract
Control code
932055312
Extent
1 online resource
Form of item
online
Isbn
9780128026311
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
http://library.link/vocab/ext/overdrive/overdriveId
9780128026311
Specific material designation
remote
System control number
(OCoLC)932055312
Label
Structure to function of G protein-gated inwardly rectifying (GIRK) channels, volume editors, Paul A. Slesinger, Kevin Wickman
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • Title page -- Table of Contents -- Copyright -- Contributors -- Preface -- Chapter One: Unifying Mechanism of Controlling Kir3 Channel Activity by G Proteins and Phosphoinositides -- Abstract -- 1 Introduction -- 2 Regulation of KACh by G Proteins -- 3 Molecular Constituents of Kir3 Channels and Physiological Roles -- 4 Dependence of KACh Channel Activity on PIPs -- 5 Physiological Significance of Distinct Membrane-Delimited Signaling Mechanisms -- 6 Molecular Mechanism of PIP2 Control of Kir Channel Gating
  • 7 Posttranslational Modification Can Control Activity Through Changes in Channelâ€"PIP2 Interactions8 The Kir3 Channel Site of GÎ2Î3 Action -- Chapter Two: The Roles of GÎ2Î3 and Gα in Gating and Regulation of GIRK Channels -- Abstract -- 1 Introduction -- 2 Interaction of Gα and GÎ2Î3 With GIRK -- 3 Roles of GÎ2Î3 and Gα in GIRK's Evoked and Basal Activity -- 4 Basal Activity of GIRKs -- 5 Multimolecular Signaling Complex and the Mechanism of GIRK Activation -- Acknowledgments -- Chapter Three: RGS Redundancy and Implications in GPCRâ€"GIRK Signaling
  • 2 Selectivity and Permeation3 Rectification -- 4 Gating -- 5 Conclusions -- Acknowledgments -- Chapter Five: Localization and Targeting of GIRK Channels in Mammalian Central Neurons -- Abstract -- 1 Introduction -- 2 Molecular Organization and Heterogeneity of GIRK Channels -- 3 Neuroanatomical Approaches to the Study of GIRK Channel Distribution -- 4 Regional Distribution of GIRK Channel Subunits in the CNS -- 5 Cellular Distribution of GIRK Channel Subunits -- 6 Subcellular Distribution of GIRK Channel Subunits
  • 7 Developmental Aspects of GIRK Channel Distribution8 Conclusions and Future Perspectives -- Acknowledgments -- Chapter Six: GIRK Channel Plasticity and Implications for Drug Addiction -- Abstract -- 1 Introduction -- 2 GIRK Channels in the Mesocorticolimbic System -- 3 Drug-Dependent Plasticity of GIRK Channel-Dependent Signaling -- 4 Mechanisms Underlying the Plasticity of GIRK Channel-Dependent Signaling -- 5 Concluding Thoughts and Future Directions -- Acknowledgments -- Chapter Seven: GIRK Channels: A Potential Link Between Learning and Addiction -- Abstract
Control code
932055312
Extent
1 online resource
Form of item
online
Isbn
9780128026311
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
http://library.link/vocab/ext/overdrive/overdriveId
9780128026311
Specific material designation
remote
System control number
(OCoLC)932055312

Library Locations

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      37.955220 -91.772210
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