Coverart for item
The Resource Translational ADMET for drug therapy : principles, methods, and pharmaceutical applications, Souzan B. Yanni

Translational ADMET for drug therapy : principles, methods, and pharmaceutical applications, Souzan B. Yanni

Label
Translational ADMET for drug therapy : principles, methods, and pharmaceutical applications
Title
Translational ADMET for drug therapy
Title remainder
principles, methods, and pharmaceutical applications
Statement of responsibility
Souzan B. Yanni
Creator
Author
Subject
Language
eng
Summary
Serving as a practical handbook about ADMET for drug therapy, this book presents effective technologies, methods, applications, data interpretation, and decision-making tactics for pharmaceutical and preclinical scientists. Chapters cover case studies and in vivo, in vitro, and computational tools for drug discovery and development, with new translational approaches to clinical drug investigations in various human populations.-Illustrates ADME properties, from bedside to bench and bench to bedside, for the design of safe and effective medicine in human populations -Provides examples that demonstrate the integration of in vitro, in vivo, and in silico data to address human PKPD and TKTD and help determine the proper therapeutic dosage -Presents successful tools for evaluating drugs and covers current translational ADMET with regulatory guidelines -Offers a hands-on manual for researchers and scientists to design and execute in vitro, in silico, preclinical, and clinical studies -Includes discussion of IND / NDA filing and drug labeling to support drug registration and approval
Member of
Cataloging source
DLC
http://library.link/vocab/creatorName
Yanni, Souzan
Dewey number
615.7
Index
index present
LC call number
RM301.5
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
QV 771
http://library.link/vocab/subjectName
  • Pharmacokinetics
  • Drugs
  • Drugs
  • Drug development
  • Chemotherapy
  • Drug Evaluation, Preclinical
  • Pharmacokinetics
  • Drug-Related Side Effects and Adverse Reactions
  • Pharmaceutical Preparations
  • MEDICAL
  • Drugs
  • Drug development
  • Chemotherapy
  • Pharmacokinetics
Label
Translational ADMET for drug therapy : principles, methods, and pharmaceutical applications, Souzan B. Yanni
Instantiates
Publication
Copyright
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Translational Concept and Determination of Drug Absorption -- Distribution: Principle, Methods, and Applications -- Metabolism: Principle, Methods, and Applications -- Excretion: Principle, Methods, and Applications for Better Therapy -- Drug-Drug Interaction: From Bench to Drug Label -- General Toxicology: Principle, Methods, and Applications -- Toxicokinetics and Toxicity Testing in Drug Development -- PBPK Modeling and In Silico Prediction for ADME and Drug-Drug Interaction -- Translational Tools toward Better Drug Therapy in Human Populations -- Phase 1-Phase 3 Clinical Studies, Procedures, Responsibilities, and Documentation -- Regulatory Submission: MIST and Drug Safety Assessment
Control code
905450321
Extent
1 online resource
Form of item
online
Isbn
9781118838419
Lccn
2015011278
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
http://library.link/vocab/ext/overdrive/overdriveId
9781118838327
Publisher number
EB00665390
Specific material designation
remote
System control number
(OCoLC)905450321
Label
Translational ADMET for drug therapy : principles, methods, and pharmaceutical applications, Souzan B. Yanni
Publication
Copyright
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Translational Concept and Determination of Drug Absorption -- Distribution: Principle, Methods, and Applications -- Metabolism: Principle, Methods, and Applications -- Excretion: Principle, Methods, and Applications for Better Therapy -- Drug-Drug Interaction: From Bench to Drug Label -- General Toxicology: Principle, Methods, and Applications -- Toxicokinetics and Toxicity Testing in Drug Development -- PBPK Modeling and In Silico Prediction for ADME and Drug-Drug Interaction -- Translational Tools toward Better Drug Therapy in Human Populations -- Phase 1-Phase 3 Clinical Studies, Procedures, Responsibilities, and Documentation -- Regulatory Submission: MIST and Drug Safety Assessment
Control code
905450321
Extent
1 online resource
Form of item
online
Isbn
9781118838419
Lccn
2015011278
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
http://library.link/vocab/ext/overdrive/overdriveId
9781118838327
Publisher number
EB00665390
Specific material designation
remote
System control number
(OCoLC)905450321

Library Locations

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      400 West 14th Street, Rolla, MO, 65409, US
      37.955220 -91.772210
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